Jacob Pitzer
English 1A
Professor Mitchel-Wagner
27 March 2014
Human Cloning: Advancement or Destruction?
Since the time that humans came to exist on this planet, we as a race have always tried to take the next step forward for progress. Over time we went from small hunter gathering bands. From small villages of people to large cities that seated empires that stretched across the continents. We as a race have always marched forward to achieve greater and greater feats for our people. However, when these feats potentially undermine who we are as a race of sentient beings; we need to shy away from such endeavors. History also shows us that advances in technology can cause death, despair, and desolation. Look at the first Word War; there were many technological advances that later had a positive benefit to humanity, but came at a very high price in human life. The Second World War showed similar advances in technology, but again, at a terrible cost. It is from these perspectives that we must stand back and examine the entire picture and what implications it holds for all of humanity. These feats in technology do not always come at the heels of war, but at the deeper understanding of science. In the 1990's, a project was commissioned to map and code the entire human genome. The implications were unimaginable; for the first time scientists would be able to identify what causes cancer, and what gene codes for what. For the first time, people with genetic diseases had some hope that they would be able to lead normal lives. But there was still detractors; those who saw this as a way for the government of corporation to own human genes, and essentially, human life. This did not come to fruition thankfully but the battles fought over Biological Engineering were not far from over. Today there are still battles on genetically modified organisms, which are used to create crops that have higher yields, or are resistant to a certain type of pest or pesticide. While science has definitively proven that these types of foods and animals are harmless to the general public, there is still a group of people that believe otherwise. But what if scientists were to expand their effort outside of plants and animals, what if they decided to artificially replicate another organism? They did, Dolly the sheep was the first cloned organism in the history of the planet (that we know of) and her existence raised controversy over whether or not it was ethical to even create her. But how far is far enough? There has to be a line set somewhere, a point in which the human community says the thin red line lies there. That line ends before full human cloning. While it can be useful to clone and grow organs and tissues for already living people who truly need them; cloning a whole human being raises too many ethical questions. Like the sacred truth that humans are unique, or the psychological questions a cloned human might ask, like "who am I" "Where do I come from". Animals do not ask these questions, nor do they care. People on the other hand have a sense of who they are and where they come from. If we start to manufacture and clone humans on a large scale, than what does that say about the sacredness of life? We must reject the ideas that this will lead to human progress, in reality it will do the opposite, lead to our destruction. In compiling evidence for this project I carefully selected sources from the library, or the library database for web sources. Reliability is key, the internet and certain print based sources might not be scholarly reviewed, or reliable to say the least. The texts that were chosen were all peer reviewed, cited sources appropriately, and were completed by respected scientists and academics alike. By using these sources, the reader can be assured that the conclusion was not drawn about under false pretenses, and that the sources used presented evidence that allowed me, the author, to draw a logical conclusions based upon the texts. Researching the topic was not very strenuous, as there is a multitude of sources available on all aspects of the topic. I started on scientific sources that would explain and detail what cloning is, and the different types of cloning that exist. In order for me to take a justifiable position, I must define what cloning is and the process of cloning. From there my position can be justified by demonstrated knowledge of the topic. Defining cloning isn't enough for justifying a position, there needs to be more evidence to back my claim that it is harmful for the human race. Bioethics is a field in medicine that focuses upon whether or not certain practices are justifiable or not. Luckily cloning is one of those topics that receives constant appraisal on whether it's valuable or harmful to society. A search for bioethics led me to a vast quantity of books and articles that were able to help me justify my position on human cloning. While not completely necessary, examples of cloning are helpful to the argument of the paper. Since Dolly the sheep is the most famous cloned organism, likely because she was the first, she becomes an important part of the paper. An examination into her life and whether or not she was worse or better off because she was cloned. A detail of her possible health problems or lack of is also critical to examining cloning on a larger scale. However she was a sheep, and sheep do not operate the same way as humans do, and likely could seriously care less about who her parents and brothers and sisters are. Nevertheless, her picture and important details about her life will serve a purpose on the topic of human cloning.
The most common method, and the method used to clone Dolly the sheep is called somatic cell nuclear transfer. The process works like this in a nutshell: a somatic cell is taken from an organism one wishes to clone. Another cell, an egg cell, or oocyte, is taken from a female of the same species. The nucleus, which contains the DNA of the original animal, is taken from the somatic cell while the rest of the cell is discarded, as it has no more use in the cloning process. The nucleus of the egg cell, or oocyte is also removed, but the rest of the cell is needed to keep the process going. The DNA of the somatic cell is then inserted inside of the egg cell. The egg cell that now contains the DNA of the other organism is shocked with electricity in order to start dividing like a normal egg cell. After being placed into a growth culture, the egg cell will form a blastocyst, which is a very early stage embryo, this embryo will be placed inside the womb of another organism where it will grow like any other offspring. However it will be genetically identical to the organism which the somatic cell was first taken from (sciencedaily.com). Below you will find a visual diagram of somatic cell nuclear transfer. The diagram appropriately uses a sheep, as Dolly the first animal cloned using this method, was a sheep.
Exhibit 1
As mentioned earlier, the first known case of successful cloning came from Scotland. A team led by Dr. Ian Wilmut was successful in using somatic cell nuclear transfer to create Dolly. This breakthrough, was highly controversial. It was met with considerable press coverage, highlighting the significant scientific breakthrough, as well as the ethics of cloning another organism. Immediately after the announcement of the cloning of Dolly, the general public quickly turned to the idea that this process could be replicated in humans. In an interview with Ian Wilmut, the head scientist on the team that cloned Dolly the sheep stated that he himself was against the cloning of humans. He was quoted as saying "I am uncomfortable with copying people, because that would involve not treating them as individuals. And so I posed the question that I would like to ask anybody who is contemplating such a use: 'do you really believe that you would be able to treat that new person as an individual' (Klotzko 24)? Dr. Wilmut is correct. One must ask how can a clone be an individual? They are genetically identical to another being. Who are they? Are they the original individual, a sibling, a child? People today stammer on about identity and how to hone in on it, but how can you do that with someone who is almost exactly the same as another? It cannot be done. In order to leave the debacle and possible psychological torment away from a future human clone, the ethical thing to do would be to just not clone someone at all. Wilmut furthered his explanation within a book he authored with Roger Highfield. Wilmut explains the psychological aspects of being a cloned human, more specifically being the clone of Wilmut himself. After Wilmut cloned Dolly Scientists, the media, and skeptical people all asked Dr. Wilmut: Will you clone yourself? The answer was a resound and effective No. Wilmut explains as to why cloning of himself of any other person would be unethical. Wilmut explains "Living in my shadow would be intolerable. Even though the reality is that a clone would be an individual living his own life, he would have to deal with the expectations of parents, family, friends, teachers and of course the media. That would be a heavy burden" (Wilmut 37). Wilmut explains even further as to what that would mean personally to the teenager. Wilmut then says "Imagine what a broody teenager would make of being told he is a genetic cop of a parent, let alone a cloner. Imagine what it would be like to know that you are the product of a scientific experiment. Imagine his irritation to learn from his pals that his father-also his brother- was called Wilf at school and that this would perhaps make a good nickname for him too" (Wilmut 37). Wilmut hit this one right on the head again. Scientists must consider what it must feel for that clone. They will ask, who am I? Am I this person, or am I me. Taking into consideration what the background of the donor cell might be, society may possibly be setting up the clone to fail. If their parent was a rapist, will they think "is it my destiny to be a rapist" and then act upon it thinking that this is just who they are. If the cell comes from a purebred genius, will they be expected to go into the field of the donor? What if they want to be something else? Will society allow for this? Cloning will give individuals the idea that they have a pre-determined destiny of sorts, and will not consider that they have a choice in the matter. They won't understand that because the idea of uniqueness and the choice of the individual will mean nothing, because they have neither. It is better to leave this implications out by simply not creating them in the first place, plain and simple. A second question society must ask is what is the point of cloning a whole human being in the first place? The only reason one can think of is to strut about the world stage and show everyone "look what I made". If there is no tangible reason for doing something so strenuous and difficult, why even bother in the first place? In a book authored by Leon Kass and James Q. Wilson; Wilson points out the argument as to why whole human cloning should be done, and how alternative methods would be better suited as a substitute for whole human cloning. Wilson explains that "The limited argument in favor of it arises from circumstances in which the husband and wife cannot conceive a child, in either the uterus or the petri dish. Cloning would thus be a substitute for either adoption, surrogate motherhood, or in vitro fertilization using cells from an unknown donor" (Wilson 100). Wilson is pointing out that there are other methods of conceiving a child that are far more effective and preserve the genetic diversity of humanity. Furthermore with this argument now ruled out in favor of easier and practical methods that preserve the individual identity of human beings, we no longer have a reason to research and apply the uses of reproductive cloning in humans.While cloning whole human beings is not a path humanity wants to walk, banning cloning altogether may halt medical advancement. One might ask what is the justification? Cloning does not necessarily mean creating whole organisms, the practice can extend to cloning organs or cells, which can be used to treat lethal medical problems. While the central argument here is that whole human cloning is a terrible idea, the purpose of this paper is to inform the public about a situation which it knows little about, and would be better off understanding the process. As a society, we should advocate for cloning of cells and organs and other bodily structures that could help our health or save us from a terrible illness. The difference between this type of cloning and whole human cloning is that the organs are generally ours. How mind blowing would it be that instead of being reliant upon others organs, scientists could grow a new one that had your dna. The idea is liberating in a sense. However the general public does not realize that cloning can involve tiny cells, but they do know that it involves large living creatures like sheep, and people. In the aftermath of the announcement of Dolly's cloning, legislatures around the United States went to work passing laws banning the use of cloning. What they did not realize, is that cloning does not necessarily mean cloning whole organisms. Andrea Bonnicksen noted in an article that "The effort to push an anticloning bill through the U.S Congress seriously miscalculated the strength of interest group politics, when more than seventy biotechnology, medical, and patient advocacy groups held press conferences and argued before Congress that efforts to discourage reproductive cloning made sense, but that a broadly worded ban would stymie medical research geared to treating diseases and conditions" (Bonnicksen 4). Experts in the biotechnology/medical field also feel that research into somatic cell nuclear transfer processes can be very beneficial. But remember, use of the process does not mean recreating a live human, it can be used and implemented to find cures and solutions to various genetic abnormalities. In an article in the New England Journal of Medicine written by Jerome P. Kassirer and Nadia A. Rosenthal; both scientists agree that there is benefits to cloning technologies, without going into detail about what negatives might exist. Regardless, they specifically discussed various ways this technology can be useful in the biotechnology field. They write "Research on somatic-cell nuclear transfer might yield numerous benefits. Studies of stem-cell differentiation could provide valuable information about the mechanism of aging or the causes of cancer. Stem cells derived from this technology might also be a rich source of material for transplantation if specific genes or sets of genes in these pluripotent stem cells could be activated and if, as has been described before, the cells could then be coaxed to differentiate" (Kassirer, Rosenthal 1). There are, as I have stated earlier, practical uses of cloning. We should not be afraid of the science, we should be afraid of those who wish to use it to further their fame. With this technology we can grow organs, code new proteins for those who have genetic abnormalities, and extend life beyond what our bodies can give us naturally. The ability to manipulate these traits will give us the advantage to nature in the sense that cancer is no longer a death sentence. AIDS will no longer be a problem because we can code for the protein that fights AIDS, which 1% of the population has. There is so much we can do for the human race using applications of cloning. However, we must not allow these efforts to cloud our conscious as to how far we can go. We must always ask ourselves is this right? Will this adversely affect the human condition? These questions when answered will allow us to understand what is beneficial, and what isn't.
Human cloning is a very controversial topic. The science says it's possible and can lead to a world without genetic diseases and ailments. Religion says life is the work of god, and scientists and business people do not have a right manipulating the will of god to their own needs. I agree with the religious community to an extent. Full human cloning is not something we need to endeavor to do. However, it is necessary for Bio/medical engineering to continue to achieve breakthroughs in the field simply because if we can do something about it, it should not be ones fate to die because they were dealt a bad pair of genes. We must limit our ambitions to simply trying to improve the livelihood of those who are born naturally. There is no need to build "Grand Armies" that we see in movies like Star Wars. Also, we must consider what this means about what we think about life, especially since we are not sure whether or not life is some fluke that happened just on Earth; while rather unlikely we still need to defend the sanctity of life. In the end, with the research and facts presented, there is a solid and irrefutable case that full human cloning can only lead to the degradation of society. If we are to preserve our society's, and keep the diversity that most people love to scream and make a big deal about, than human cloning is simply not a road we must go down. In order to keep the human race unique and free, we must reject the idea that cloning human beings, is a part of the evolution of our race. However if we truly want to evolve past what we are now, it would make more sense to keep the genetic diversity we have today coupled with medical advances that can cure genetic ailments, cancer, AIDS, and all other types of genetic abnormalities. It is our differences that make us who we are and shape the relationships between those we love and our dear friends. If science dares to destroy these bonds than I fear that the human race will be different in the negative. Using Cloning technology to advance our abilities for those who were born naturally is common sense. Using it to create large products of people that share the same DNA will only lead to the loss of the individual, and the loss of the human condition.
Works Cited
Kass, Leon, and James Q. Wilson. The Ethics of Human Cloning. Washington, D.C.: AEI, 1998. Print. Kassirer, Jerome P., and Nadia A. Rosenthal. "Should Human Cloning Research Be Off Limits?" New England Journal of Medicine 338.13 (1998): 905-06. Print.
Klotzko, Arlene Judith. The Cloning Sourcebook. Oxford: Oxford UP, 2001. Print.
MacKinnon, Barbara. "Crafting Cloning Policies." Human Cloning: Science, Ethics, and Public Policy. Urbana: University of Illinois, 2000. N. pag. Print.
"Somatic Cell Nuclear Transfer." ScienceDaily. ScienceDaily, n.d. Web. 31 Mar. 2014.
"Somatic Cell Nuclear Transfer." Somatic Cell Nuclear Transfer. N.p., n.d. Web. 01 Apr. 2014.
Wilmut, Ian, and Roger Highfield. After Dolly: The Uses and Misuses of Human Cloning. New York: W.W. Norton &, 2006. Print.